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Allergy

Carmine is used as a food dye in many different products such as juices, ice cream, yogurt, and candy, and as a dye in cosmetic products such as eyeshadow and lipstick. Although principally a red dye, it is found in many foods that are shades of red, pink, and purple. As a food dye it has been known to cause severe allergic reactions and anaphylactic shock in some people.[1] [2] Food products containing carmine-based food dye may prove to be a concern for people who are allergic to carmine, or people who choose not consume any or certain animals, such as vegetarians, vegans, and followers of religions with dietary law (e.g. kashrut in Judaism and halaal in Islam).

Description

Carmine Carmine (pronounced /ˈkÉ‘rmɪn/, English pronunciation: /ˈkÉ‘rmaɪn/, or /ˈkÉ‘rmiːn/), also called Crimson Lake, Cochineal, Natural Red 4, C.I. 75470, or E120, is a pigment of a bright red color obtained from the carminic acid produced by some scale insects, such as the cochineal and the Polish cochineal, and is used as a general term for a particularly deep red color of the same name. Carmine is used in the manufacture of artificial flowers, paints, rouge, yoghurt, cosmetics, food additives, and crimson ink.

European Union

In the European Union, the use of carmine in foodstuffs is regulated under the European Commission's directives governing food additives in general ([3], [4]) and food dyes in particular ([5]) and listed under the names Cochineal, Carminic acid, Carmines and Natural Red 4 as additive E 120 in the list of EU-approved food additives ([6]). The directive governing food dyes approves the use of carmine for certain groups of foodstuffs only (a list of approved uses is included in Annexes I and III of EU-Directive 94/36 [7]) and specifies a maximum amount which is permitted or restricts it to the quantum satis. The EU-Directive 2000/13/EC [8] on food labeling mandates that carmines (like all food additives) must be included in the list of ingredients of a food product with its additive category and listed name or additive number, that is either as Food colour carmines or as Food colour E 120 in the local language(s) of the market(s) the product is sold in. Although concerns of hazards from allergic reactions were raised, the use of carmine in foodstuffs is not banned in the EU. However, the use of carmine in foodstuffs has been discouraged by European food safety authorities, and although it is predominately used as colouring in alcoholic beverages, it can still be found in foods such as supermarket Indian curries. A re-evaluation process of the approval status of several food colours (including carmine) was started by the Panel on food additives, flavourings, processing aids and materials in contact with food of the European Food Safety Authority in early 2006 and is scheduled to be completed by 2008 ([9] Accessed on 2 January 2007, [10])

Production

The quality of carmine is affected by the temperature and the degree of illumination during its preparation, sunlight being requisite for the production of a brilliant hue. It also differs according to the amount of alumina present in it. It is sometimes adulterated with cinnabar, starch and other materials; from these the carmine can be separated by dissolving it in ammonia. Good carmine should crumble readily between the fingers when dry. Carmine lake is a pigment obtained by adding freshly precipitated alumina to decoction of cochineal. Carmine can be used as a staining agent in microbiology, as a Best's carmine to stain glycogen, mucicarmine to stain acidic mucopolysaccharides, and carmalum to stain cell nuclei. In these applications, it is applied together with a mordant, usually an Al(III) salt.

References

* Amy Butler Greenfield – A Perfect Red: Empire, Espionage, and the Quest for the Color of Desire, Harper Collins, 2005. ISBN 0-06-052275-5 * This article incorporates text from the Encyclopædia Britannica, Eleventh Edition, a publication now in the public domain.

United States

In the United States, carmine is approved as dye for foodstuffs. In January 2009, FDA passed a new regulation[3] requiring carmine and cochineal to be listed by name on the label. This regulation is effective January 5, 2011. In January 2006, the FDA evaluated a proposal[4] that would require food products containing carmine to list it by name on the ingredient label. It was also announced[citation needed] that the FDA will separately review the ingredient labels of prescription drugs which contain colorings derived from carmine. A request from the Center for Science in the Public Interest (article titled: "FDA Urged to Improve Labeling of or Ban Carmine Food Coloring" http://www.cspinet.org/new/200605011.html [1])[citation needed] to require ingredient labels to explicitly state that carmine may cause severe allergic reactions and anaphylactic shock and that is derived from insects was declined by the FDA. Food industries were aggressively opposed to the idea of writing "insect based" on the label and they finally agreed to simply putting "carmine"[citation needed]. Although concerns over hazards from allergic reactions have been asserted,[citation needed] the United States Food and Drug Administration agency (FDA) has not banned the use of carmine and states it found no evidence of a "significant hazard" to the general population.[2] This is not to say that the dye does not pose a significant hazard to some people.